Professor Kuku is currently President, African Academy of Sciences and Distinguished Professor of Mathematics and Computational Science at the Botswana International University of Science and Technology. He was Professor of Mathematics at the International Centre for Theoretical Physics, Trieste Italy, 1995-2003, and William .W. S. Claytor Endowed Professor of Mathematics, Grambling State University, Louisiana, USA . He has held many Visiting Positions at reputable Universities and Research Institutes in the USA, Canada, Europe, HongKong, China including, Member, Institute for Advanced Study, Princeton, NJ 2003-2004; Visiting research Professor, mathematical Sciences Research Institute, Visiting Professor Cornell University, etc. He has had long research and teaching Experience at University level since 1965 and was Head Mathematics Department, Dean Post Graduate School, University of Ibadan in Nigeria. He was President of the African Mathematical Union for nine years  1986-95.

Professor Kuku is one of the world leaders in several aspects of K-theory and connections to commutative and non-commutative Algebra/Number theory/Geometry/Representation theory-a contemporary and multidisciplinary subject that also have applications in mathematical physics, Dynamical systems, Econometrics and Control theory. He has 85 publications made up of 52 research articles in highly reputable journals; 10 books/monographs and 23 articles on topical issues in mathematical research and education, science, and technology. He has supervised and mentored many young mathematicians at Masters, Doctoral and Post-Doctoral levels.

Professor Kuku is a recipient of several honours: He is a Fellow of the American Mathematical Society, 2012-; Fellow of The World Academy of Sciences (TWAS) (1989 -); European Academy of Arts, Science and Humanities (1986 - ); African Academy of Sciences(AAS) (1986 - ); Nigerian Academy of sciences (1989 - ); Foreign fellow, Mongolian Academy of Sciences (2005 -); Honorary President (AMU) for life;(1995- );Nigeria National Honours: OON (Officer of the Order of the Niger) 2008-;NNOM (Nigerian National Order of Merit)2009; —the highest honour in Nigeria for academic excellence. An International conference on “Algebraic K-theory and its applications” March 17-21 2011 was organised by Nanjing University, China in honour of his 70th birthday, and a special issue of the Journal of K-theory, Volume 12, no 1, published by the Cambridge University Press, UK recently appeared as Proceedings of the conference.