Biography


Prof. K P Sharma
University of Rajasthan, India
Title:
Spirulina Role in Mitigation of Haemato-toxicity in Swiss Albino Mice Exposed to Aluminum and Aluminum Fluoride
Abstract:
Toxic effects of aluminum (sub-acute: @78.4 mg / kg body weight for 7 days, sub-chronic: @7.8 mg / kg body weight for 90 days) and aluminum fluoride (sub-acute: @103 mg / kg body weight, sub-chronic: @21mg / kg body weight) are reported on the haematology of male Swiss albino mice along with alleviating effects of diet supplement Spirulina (@230 mg / kg body weight). The recovery of treated mice (sub-chronic groups) was also studied for another 90 days. Blood samples were analysed using a Sysmex KX 21 cell counter. Differential leucocyte counts and morphological abnormality in erythrocytes were quantified. There were significant alterations in values of RBC (↓ 5-18%), Hb (↓15-17%), PCV (↓ 8-14%), WBC (↑54-124%) and platelets (↓ 26-36%), more particularly after sub-acute exposure. Morphology of RBC was also distorted. Aluminum fluoride was comparatively more toxic than aluminum. Spirulina supplement alleviated chemicals toxicity.
Biography:

He joined as a faculty member in the Botany Department, Rajasthan University in Nov. 1977 and at presently serving as Professor in Botany. He has been a Visiting Scientist in the CSIRO, Division of Water Resources, Australia (1991-92) where He worked on low –cost wastewater treatment for sewage. 23 research students have obtained their Ph.D. degree under his supervision; two have submitted their thesis and 8 are registered for Ph.D. He has various Government of India sponsored scientific projects and findings of them are of great relevance to the society, as mentioned below. 

Scientific Achievements 

1. Obtained Ph. D. on the “Ecology and Management of Wetlands” in and around Jaipur in 1978. 

2. Studied on limnology ( ecological studies of freshwater water body) of water bodies in and around Jaipur such as Mansagar, Ramgarh, Durgapura impoundment, Shivdaspura and Keola deo national park , Bharatpur 

3. Studied on Sambhar lake (saline lake) and authored a book published by WWF, India. 

4. Wrote review articles on the ecology of aquatic vegetation in India, Pakistan, Bangaldesh and Sri Lanka which are published in an edited book “ Ecology and Management of Aquatic Vegetation in the Indian Subcontinent” Kluver Publ., the Netherland. 

5. A monograph on “Water- hyacinth: The Most Troublesome weed of the World”. Hindasia Publication, New Delhi. 

6. Book on “Environmental Guidelines and Standards in India. 

7. He is a reviewer of scientific articles published by other scientists in Magazines on Environment and Biotechnology, published in India and abroad. 

8. He is a reviewer of scientific projects submitted by scientists in MOEF, New Delhi, DST, New Delhi and DBT, New Delhi and a member of Expert Advisory Committee , State DST, Jaipur. 

Mile Stones 

1. The low-cost technology for bioremediation of Textile Dye wastewaters of Textile Industry at Sanganer has been demonstrated at pilot scale with financial support of Department of Biotechnology, Ministry of Science & Technology, New Delhi and Rajasthan Chamber of Commerce & Industry, Jaipur. This technique has been patented by the Government of India, New Delhi. 

2. Bioremediation of polluted water of duck pond at S.M.S. School, Jaipur is being done for almost 5 years in a system designed by me. This system is treating 13,000L polluted water on alternate day used for gardening. 

3. Developed a low-cost technology for treating distillery waste with financial support of Department of Biotechnology, Ministry of Science & Technology, New Delhi. 

4. Worked on bioremediation of Mansagar lake (Jalmahal) in collaboration of Jaipur Development Authority, Jaipur. We are designing kidney of this lake (60% completed); a unique approach first used in our country. 

5. Using biomanipulation, treated a small polluted water body (5 hectare) adjoining Mansagar lake. The water of this water body has become almost clean within 4 years. This technique may be replicated in other water bodies at a minimal expenditure. Presently detailing the biomanipulation process at the bench scale in the laboratory. 

6. A new approach for controlling Prosopis juliflora (Vilayti babool) in the lake bed has been developed. Since its application, no regeneration of juliflora has been noted in the lake bed for last three years. 

7. An effective use of biomass of marshy species by the locals has been promoted without compromising their functions along the Mansagar bank. This has reduced pressure of locals on the nearby forest for fodder, thatching material as well as fuel. 

8. Also working on minimizing sufferings of mankind due to fluoride toxicity in animal models. Findings are very interesting and may find application in fluoride affected areas in the country.

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